Fatty acid amide hydrolase substrate specificity.
نویسندگان
چکیده
Fatty acid amide hydrolase (FAAH), also referred to as oleamide hydrolase and anandamide amidohydrolase, is a serine hydrolase responsible for the degradation of endogenous oleamide and anandamide, fatty acid amides that function as chemical messengers. FAAH hydrolyzes a range of fatty acid amides, and the present study examines the relative rates of hydrolysis of a variety of natural and unnatural fatty acid primary amide substrates using pure recombinant rat FAAH.
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 10 23 شماره
صفحات -
تاریخ انتشار 2000